Glucosamine & Chondroitin

Glucosamine and chondroitin are natural substances most often used together to treat arthritic conditions. There is medical evidence that together these ingredients can reduce the pain and stiffness found in joints, and that they can stop or reverse the effects of arthritis. Glucosamine and chondroitin help repair and prevent the further breakdown of cartilage while helping to create new cartilage and other body tissues. They have anti-inflammatory properties to help improve movement and relieve pain.

“The consensus of expert and industry opinions supports the use of chondroitin and its common partner agent, glucosamine, for improving symptoms and stopping (or possibly reversing) the degenerative process of osteoarthritis”
- Mayo Clinic

“Research studies tell us that more than half the people with osteoarthritis taking glucosamine and chondroitin improve. They have less pain and better movement”
- U.S. Department of Health & Human Services | Agency for Healthcare Research & Quality

“For a subset of participants with moderate-to-severe pain, glucosamine combined with chondroitin sulfate provided statistically significant pain relief compared with placebo”
- National Institutes of Health |National Center for Complementary and Alternative Medicine

“Available evidence from randomized controlled trials supports the use of glucosamine sulfate in the treatment of osteoarthritis, particularly of the knee”
- Medline Plus | U.S. National Library of Medicine | National Institutes of Health

“Results from several well-designed scientific studies suggest that chondroitin supplements may be an effective treatment for OA, particularly OA of the knee or hip. In general, findings from these studies suggest that chondroitin: Reduces OA pain, Improves functional status of people with hip or knee OA, Reduces joint swelling and stiffness, Provides relief from OA symptoms for up to 3 months after treatment is stopped”
- University of Maryland Medical Center

MSM

MSM plays an important role in joint health and helps form cartilage, tendons and ligaments to improve motion and comfort to more easily perform daily activities.

“MSM is important in joint health and helps form connective tissue (cartilage, tendons, and ligaments). It may also slow the nerve impulses that transmit pain signals, reducing pain”
- University of Maryland Medical Center

“MSM also produced improvement in performing activities of daily living when compared to placebo”
- PubMed | U.S. National Library of Medicine | National Institutes of Health

Cetyl Myristoleate (also known as CM8)

Cetyl Myristoleate (also known as CM8) lubricates joints to help them move smoothly and reduce stiffness. It contains anti-inflammatory properties to reduce swelling in joints. Cetyl Myristoleate is also an immune system modulator, and can help fight arthritic conditions while providing pain relief. The effectiveness of Cetyl Myristoleate was confirmed by the San Diego Clinic Immunological Center and was published in the American Journal of Pharmaceutical Sciences.

Bromelain

Bromelain is a mixture of enzymes that contain anti-inflammatory properties. It is found in many natural pain remedy supplements, working to reduce inflammation and the pain that comes with it.

“When taken with meals, bromelain is believed to assist in the digestion of proteins. When taken on an empty stomach, it is believed to act medicinally as an anti-inflammatory agent”
- Medline Plus | U.S. National Library of Medicine | National Institutes of Health

“Preliminary studies suggest that bromelain may also help reduce pain associated with rheumatoid arthritis”
- University of Maryland Medical Center

“Several preliminary studies suggest that when taken by mouth, bromelain can reduce inflammation or pain caused by inflammation”
- Medline Plus | U.S. National Library of Medicine | National Institutes of Health

Beta-Carotene

Beta-Carotene boosts the immune system and helps increase fluid in the joint lining. It is an important part of bone growth and possesses antioxidant properties. Beta-carotene is converted into Vitamin A once ingested.

“Vitamin A is a family of compounds that play an important role in vision, bone growth, reproduction, cell division, and cell differentiation”
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases

Calcium

Calcium is essential for the formation of bones and teeth. It is also required for blood clotting, muscle contraction, and the transmission of signals in nerve cells. Calcium is widely known for its prevention of osteoporosis.

“Older women need plenty of calcium to prevent osteoporosis. People who do not eat enough high-calcium foods should take a calcium supplement.”
- Medline Plus | U.S. National Library of Medicine | National Institutes of Health

“Calcium is required for muscle contraction, blood vessel expansion and contraction, secretion of hormones and enzymes, and transmitting impulses throughout the nervous system.”
- Office of Dietary Supplements | National Institutes of Health

Pine Bark

Pine Bark is a powerful antioxidant with anti-inflammatory properties that reduces pain while improving the physical function of joints. Pine Bark also helps replace degenerated cartilage.

“Proponents claim that pine bark extract is a powerful antioxidant. Antioxidants are compounds that block the action of free radicals, activated oxygen molecules that can damage cells. Supporters believe pine bark extract protects against arthritis, complications from diabetes, cancer, heart disease, and problems with circulation such as swelling and varicose veins. Other reported benefits include improved memory, fewer effects from stress, better joint flexibility, and decreased inflammation”
- American Cancer Society

“In vitro and animal studies find pine bark extract has antioxidant, anti-inflammatory properties”
- Memorial Sloan-Kettering Cancer Center

“Preliminary research suggest it reduces menopausal symptoms in peri-menopausal women, and improves osteoarthritis symptoms”
- Memorial Sloan-Kettering Cancer Center

Vitamin E

Vitamin E aids in reducing joint inflammation. It is used by rheumatoid arthritis sufferers to help support joint cartilage growth.

“Vitamin E has been proposed for the prevention or treatment of numerous health conditions, often based on its antioxidant properties.”
- Mayo Clinic

“Vitamin E is an antioxidant that protects body tissue from damage caused by unstable substances called free radicals. Free radicals can harm cells, tissues, and organs. They are believed to play a role in certain conditions associated with aging.”
- Medline Plus | U.S. National Library of Medicine | National Institutes of Health

Vitamin C

Vitamin C is an antioxidant that is vital for the formation and growth of bones and connective tissues such as tendons and ligaments. It helps form collagen in bones and cartilage and helps fight infection and inflammation.

“Vitamin C (ascorbic acid) is a water-soluble vitamin, which is necessary in the body to form collagen in bones, cartilage, muscle, and blood vessels and aids in the absorption of iron.”
- Mayo Clinic

“Vitamin C (ascorbic acid) is essential for the formation, growth, and repair of bone, skin, and connective tissue (which binds other tissues and organs together and includes tendons, ligaments, and blood vessels). Vitamin C helps maintain healthy teeth and gums. It helps the body absorb iron, which is needed to make red blood cells. Like vitamin E, vitamin C is an antioxidant.”
- Merck & Co., Inc.

Boron

Boron is a natural mineral that has been used for joint pain relief for decades. It supports healthy bone structure and has anti-inflammatory properties.

“Based on human population research, in a boron rich environment, people appear to have fewer joint disorders. It has also been proposed that boron deficiency may contribute to the development of osteoarthritis”
- Medline Plus | U.S. National Library of Medicine | National Institutes of Health

Resverstrol

Resveratrol is a powerful antioxidant that halts the damage done to cartilage and speeds up recovery. It stimulates the production of key proteins that make up an important part of the connective tissue in the joints.

“Scientists across the country have identified a substance in red wine called resveratrol that they believe might do more than just protect the heart, but could in very high concentrations significantly extend life by preventing a number of age related illnesses.”
- 60 Minutes | CBS News

Magnesium

Magnesium helps keep bones strong while supporting a healthy immune system and steady heart rhythm. It is also known to assist in normal muscle and nerve function.

Hydrolyzed Collagen Type II

Hydrolyzed Collagen Type II aids in the growth of new cartilage in joints while helping to heal and repair connective tissue. It is a common proponent in rheumatoid arthritis treatments.

Hyaluronic Acid

Hyaluronic Acid is an important component of cartilage and works to cushion and lubricate the joints. It also helps reduce pain and swelling.

Emu Oil

Emu Oil reduces the swelling and inflammation of the tissue surrounding the joints and increases the mobility of the joints.